Tuberc Respir Dis > Accepted Articles
Lung cancer
DOI: https://doi.org/10.4046/trd.2020.0159    [Accepted]
Published online May 13, 2021.
Comparison of clinical and radiologic characteristics between anthracofibrosis and endobronchial lung cancer
Seo Young Yun, Tae Yun Park
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea
Correspondence:  Tae Yun Park, Tel: 82-2-870-3033, 
Email: cally0329@hanmail.net
Received: 5 December 2020   • Revised: 24 February 2021   • Accepted: 3 May 2021
Abstract
Background
Endobronchial lung cancer (EBLC) and bronchial anthracofibrosis (BAF) share similarities, including similar symptoms and radiological findings. The aim of this study was to describe clinical and radiological differentiation between BAF and EBLC, both of which were confirmed by bronchoscopy.
Methods
This was a retrospective study of patients with BAF or EBLC from 2008 to 2014. Data were derived from a bronchoscopy registry made since January 1, 2008. Clinical and radiological characteristics of both diseases were analyzed.
Results
Among 3,214 patients who underwent bronchoscopy, 167 and 117 patients were enrolled in BAF and EBLC groups, respectively. BAF occurred more predominantly in older non-smoking female patients with a higher chance of tuberculosis (38.3%) than EBLC (6.0%). Cough, sputum, and dyspnea were common symptoms reported for both groups. Bronchoscopic findings revealed that BAF lesions were more common in multiple lobar bronchi (85.0%) or bilaterally (73.7%). Radiologic findings revealed that bronchial stenosis was the most commonly found lesion in both groups (49.1% and 78.6%, respectively). Rates of peribronchial calcification and bronchial wall thickening were higher in the BAF group. The number of patients with lymph node calcification was also higher in the BAF group.
Conclusion
Results of this study demonstrated characteristics of clinical and radiologic findings of BAF and EBLC. Increasing the awareness of both diseases may help clinicians differentiate these two diseases from each other, thus avoiding unnecessary invasive diagnostic procedures.
Key Words: Bronchial annthracofibrosis, Endobronchial lung cancer, Bronchoscopy


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