Tuberc Respir Dis > Issue 17; 1964 > Article
Tuberculosis and Respiratory Diseases 1964;17:97-99.
DOI: https://doi.org/10.4046/trd.1964.17.1.97    Published online December 1, 1964.
BITHIONOL THERAPY FOR LUNG PARAGONIMIASIS
Pyoung Ki Kim, Sang BaiK Oh, Jung Hee Lee
Department of Chest Medicine, National Medical, Center
Abstract
Bithionol is a new drug which has shown good effect in paragonimiasis. The authors treated 36 cases of pulmonary paragonimiasis from June 1962 to June 1963. In all cases eggs of paragonimus westermani were found in sputum before treatment. The most characteristic symptoms; bloody sputum or frank hemoptysis, which was seen in 33 of 36 cases, disappeared completely in 10 of 14 cases especially closely checked to that effect. Laboratory findings such as leukocyte did not show significant change under Bithionol treatment, but sedimentation rate improved in about 1/2 of the cases, liver function tests did not show any change under Bithionol treatment. Of side reaction under Bithionol treatment gastrointestinal symptoms such as diarrhea, loose stools or frequent defecation was seen in 10 cases(27.7%) skin manifestations such as urticaria and itching in 7(18.4%). All the side reactions subsided when medication was continued every other day. In no case we were forced to stop medication.
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