| THE EFFECTS OF PULMONARY RESECTIONS ON THE CARDIOPULMONARY FUNCTION IN THE HYPOTHERMIC DOG |
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Goon Jik Bai |
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Department of Surgery, Scool of Medicine, Kyungpuk National University |
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| Abstract |
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A study was carried out to evaluate the effects of pulmonary resections on the cardiopulmonary function in 20 normothermic and 20 hypothermic dogs. Hypothermia was induced by body surface cooling with ice water, and dogs were rewarmed with hot water. The range of esophageal temperature was 29 ℃ to 31 ℃.
The experimental dogs were divided into two groups: group Ⅰ(20 dogs) had right pneumonectomy, and group Ⅱ (20 dogs)were resected 68% of total lung parenchyma.
Hyperventilation by means of a respirator with room air was done during cooling and thoracotomy. Lung ventilation, pressures of right ventricle, pulmonary artery, femoral artery and inferior vena cava, and cardiac output were measured. Oxygen saturation, pH and CO2 tention of arterial blood were determined. These observations were made at the stages of pre-cooling, thoracotomy, post-resection and rewarding.
Results were as follows: 1) Oxygen consumption and CO2 elimination tended to decrease in both experimental groups of right pneumonectomy and 68% resection of total lung parenchyma during hypothermia.
2) Cardiac output was markedly reduced during hypothermia followed by decrease of arterial blood pressure which would minimize bleeding during surgery, however, would be inadequate for tissue perfusion.
3) Elevation of pulmonary artery pressure was less among the 68% resected hypothermic dogs than control group. 4) One out of ten of the 68% resected hypothermic dogs died. whille three out of ten of the control dogs died. 5) Hypothermia wouldl make the surgical risk prohibitive for those who had poor pulmonary reserve or far advanced lung diseases. |
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