1. Roski J, Bo-Linn GW, Andrews TA. Creating value in health care through big data: opportunities and policy implications. Health Aff (Millwood) 2014;33:1115-22.
2. De Mauro A, Greco M, Grimaldi M. A formal definition of big data based on its essential features. Libr Rev 2016;65:122-35.
8. Lim GN, Allen JC, Tiew PY, Chen W, Koh MS. Healthcare utilization and health-related quality of life of severe asthma patients in Singapore. J Asthma 2023;60:969-80.
9. Brusselle GG, Koppelman GH. Biologic therapies for severe asthma. N Engl J Med 2022;386:157-71.
12. Dash S, Shakyawar SK, Sharma M, Kaushik S. Big data in healthcare: management, analysis and future prospects. J Big Data 2019;6:1-25.
13. Wallace PJ, Shah ND, Dennen T, Bleicher PA, Crown WH. Optum labs: building a novel node in the learning health care system. Health Aff (Millwood) 2014;33:1187-94.
15. FitzGerald JM, Tran TN, Alacqua M, Altraja A, Backer V, Bjermer L, et al. International severe asthma registry (ISAR): protocol for a global registry. BMC Med Res Methodol 2020;20:212.
17. Hennessy S, Leonard CE, Palumbo CM, Newcomb C, Bilker WB. Quality of medicaid and medicare data obtained through Centers for Medicare and Medicaid Services (CMS). Med Care 2007;45:1216-20.
18. Bolognesi MP, Habermann EB. Commercial claims data sources: PearlDiver and individual payer databases. J Bone Joint Surg Am 2022;104(Suppl 3):15-7.
26. Ryan D, Heatley H, Heaney LG, Jackson DJ, Pfeffer PE, Busby J, et al. Potential severe asthma hidden in UK primary care. J Allergy Clin Immunol Pract 2021;9:1612-23.
27. Hong SH, Cho JY, Kim TB, Lee EK, Kwon SH, Shin JY. Cost-effectiveness of tiotropium in elderly patients with severe asthma using real-world data. J Allergy Clin Immunol Pract 2021;9:1939-47.
28. Lee H, Ryu J, Nam E, Chung SJ, Yeo Y, Park DW, et al. Increased mortality in patients with corticosteroid-dependent asthma: a nationwide population-based study. Eur Respir J 2019;54:1900804.
29. Wang E, Wechsler ME, Tran TN, Heaney LG, Jones RC, Menzies-Gow AN, et al. Characterization of severe asthma worldwide: data from the International Severe Asthma Registry. Chest 2020;157:790-804.
30. Chen W, Sadatsafavi M, Tran TN, Murray RB, Wong CB, Ali N, et al. Characterization of patients in the International Severe Asthma Registry with high steroid exposure who did or did not initiate biologic therapy. J Asthma Allergy 2022;15:1491-510.
31. Scelo G, Torres-Duque CA, Maspero J, Tran TN, Murray R, Martin N, et al. Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry. Ann Allergy Asthma Immunol 2024;132:42-53.
34. Grimes DA, Schulz KF. Cohort studies: marching towards outcomes. Lancet 2002;359:341-5.
35. Wang X, Cheng Z. Cross-sectional studies: strengths, weaknesses, and recommendations. Chest 2020;158(1S):S65-71.
38. Exarchos KP, Beltsiou M, Votti CA, Kostikas K. Artificial intelligence techniques in asthma: a systematic review and critical appraisal of the existing literature. Eur Respir J 2020;56:2000521.