A Case of Epithelioid Hemangioendothelioma Involving the Lung and Liver.

Lee, Seung Keun; Choi, Seung Hyuk; Yang, Dong Gyoo; Park, Jae Min; Kim, Seong Kyoo; Lee, Won Young; Shin, Dong Hwan

doi:1997.44.6.1396

Tuberc Respir Dis > Volume 44(6); 1997 > Article

Case Report

Tuberculosis and Respiratory Diseases 1997;44(6):1396-1402.
DOI: https://doi.org/10.4046/trd.1997.44.6.1396 Published online December 1, 1997.

A Case of Epithelioid Hemangioendothelioma Involving the Lung and Liver.

Seung Keun Lee, Seung Hyuk Choi, Dong Gyoo Yang, Jae Min Park, Seong Kyoo Kim, Won Young Lee, Dong Hwan Shin

¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
²Department of Pathology Yonsei University College of Medicine, Seoul, Korea.

Abstract

Epithelioid Hemangioendothelioma(EH) is a rare vascular tumor, originating from endothelial cells. The principal locations are lung, soft tissue, bone and liver. This tumor is of borderline malignancy, relatively benign course. In the lung, the tumor is often multifocal, bilateral and frequently lead to the mistaken diagnosis of metastatic carcinoma. Although EH of the lung is relatively slow growing tumor, extensive pulmonary involvement, systemic metastasis, mainly to the liver have been documented. A 26-year-old man with EH involving the lung and liver was reported. Chest X-ray and chest CT showed multiple nodules in both lung fields and Abdominal CT multiple round low densities in liver. Transbronchial lung biopsy was performed. The patient diagnosed as EH by light microscopic finding and immunohistochemical study for Factor VIII-related antigen.

Key Words: Epithelioid hemangioendothelioma, Lung, Liver