Pulmonary Cryptococcosis.

Kim, Gye Su; Lee, Jae Cheol; Lee, Seung Jun; Yoo, Chul Gyu; Kim, Young Whan; Han, Sung Koo; Shim, Young Soo

doi:1996.43.1.113

Tuberc Respir Dis > Volume 43(1); 1996 > Article

Case Report

Tuberculosis and Respiratory Diseases 1996;43(1):113-116.
DOI: https://doi.org/10.4046/trd.1996.43.1.113 Published online February 1, 1996.

Pulmonary Cryptococcosis.

Gye Su Kim, Jae Cheol Lee, Seung Jun Lee, Chul Gyu Yoo, Young Whan Kim, Sung Koo Han, Young Soo Shim

Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine, Seoul, Korea.

Abstract

A previously healthy 59-year old male patient was admitted due to cough and abnormal chest x-ray. Cough started 5 months ago and persisted. Two months before admission, abnormality in chest PA was detected. He had no symptom other than cough. He was nonsmoker and physical examination revealed no abnormal finding. His chest X-ray showed ill-defined 2x1 cm ovoid infiltration in left middle lung field. On chest computed tomography, it was located in the subpleural region of posterobasal segment of left lower lobe. Mediastinal lymphadenopathy was absent. Blood test and sputum examination were not diagnostic. Fluoroscopy-guided percutaneous needle biopsy revealed pulmonary cryptococcosis. After central nervous system involvement was excluded by spinal tap, oral ketoconazole therapy was started. The lesion decreased in size after 8 weeks of therapy and almost disappeared on follow-up chest X-ray 4 months later.

Key Words: Left lower lobe infiltration, PCNB, Pulmonary cryptococcosis