The Clinical effects of PZA-INA combined therapy for the advanced Pulmonary Tuberculosis Patients following long-term Chemotherapy

Yoo, Kwang Hyun; Chang, Pyung Ha; Oh, Phil Mo

doi:1960.0.9.38

Tuberc Respir Dis > Issue 9; 1960 > Article

Tuberculosis and Respiratory Diseases 1960;9:38-40.
DOI: https://doi.org/10.4046/trd.1960.9.1.38 Published online December 1, 1960.

The Clinical effects of PZA-INA combined therapy for the advanced Pulmonary Tuberculosis Patients following long-term Chemotherapy

Kwang Hyun Yoo, Pyung Ha Chang, Phil Mo Oh

Transportation Recuperation, Masan, Korea

장기화학요법을 시행해 오던 중증폐결핵환자에 대한 PZA INH병합요법의 임상효과

유광현, 장병하, 오필모

Abstract

The results have been presented of the PZA-INH treatment in a group of 22 patients with far advanced, cavitating pulmonary tuberculosis. These Patients had previously received long-term chemotherapy inc1udipg INH. (1) The radiological evaluations were not impressive, and there were only 4 case3 showing slight improvement, 3 cases deteriorated after 5-6 months of PZA-INH treatment. (2) The occurrence of negative sputum over 6 months was observed in 5 patients, among which 3 case3 showed recurrence of positive sputum after 8-9 months of negativity. (3) Among 12 patients, 6(50%) had a decrease in cough, 9(75%) had a decrease of expectoration, 4(33%) had an increase in appetite, 2 (17%) had an increase in weight and 2 febrile case3 (38℃), the temperature returned to normal in 1-2 months of treatment. (4) Evaluating the side reactions : 3 case3 showed mild joint pain for a short period and 1 case developed jaundice after 5 months of treatment.