Clinical Observation on the Treatment of Pulmonary Paragonimiasis with Dionol

Oh, Hyun Kwan; Kim, Hi Seup; ,; ,; ,

doi:1962.0.14.33

Tuberc Respir Dis > Issue 14; 1962 > Article

Tuberculosis and Respiratory Diseases 1962;14:33-36.
DOI: https://doi.org/10.4046/trd.1962.14.1.33 Published online December 1, 1962.

Clinical Observation on the Treatment of Pulmonary Paragonimiasis with Dionol

Hyun Kwan Oh, Hi Seup Kim

College of Medicine, Ewha Woman's University, Seoul, Korea

DIONOL[2.2`-thiobis (4.6-dichlorophenol)]에 의한 인체폐충증의 임상치료실험(제1보)

오현관, 김희섭, 경란호, 김재섭, 이온영

Abstract

This survey consists of 12 pulmonary paragonimiasis cases which were proved by the detection of the ova in the sputum as well as clinical symptoms. The patients in this study were divided into two groups according to the dosage given of the drug, Djonl. Nine cases were treated with 30 mg/kg, and three cases 20 mg/kg. Each group were treated with the drug every other day in a period of 12 days. Follwing results were obtained: (1) In 7 of 12 cases, 58.3%, the bloody sputum disappeared in the fourth day after beginning of the treatment. The others in the 8-10th day. (2) The eggs in the sputum were cleared in the 8-12th day in all cases. Three of the 12 cases, 25%, in the sixth day. (3) No signification difference was observed between the group of 30 mg/kg and of 20 mg/kg. (4) In about 50% of all cases, the X-ray findings of cloudy density (1 pneumonitis) were disappeared or improved. (5) No clinical evidence of recurrence was seen in the following two methods after treatment.