A Study of Resistance to Primary Drugs in In-patient

Oh, Joong Keun

doi:1975.22.4.158

Tuberc Respir Dis > Volume 22(4); 1975 > Article

Original Article

Tuberculosis and Respiratory Diseases 1975;22(4):158-164.
DOI: https://doi.org/10.4046/trd.1975.22.4.158 Published online December 1, 1975.

A Study of Resistance to Primary Drugs in In-patient

Joong Keun Oh

Department of Chest Medicine, the Nationa! Medica! Centre, Korea.

폐결핵환자의 입원시 일차약제 내성에 관한 연구

오중근

Abstract

During three years from November 1958 to December 1961, we observed and analyzed fo r bacteriological study in terms of primary (standard triple) drug resistance in randomly selected 207 actíve pulmonary tuberculosís cases who were hospitalized to the chest departmen t in N.M.C. and resuits were as follows : 1. Sex and age dístribution ín this study was 129 male an d 78 female. The pealk was 29-30 years of age group 67.6% of the total Thís is specially signíficant because thís age group is most actíve sociall y and ín terms of labor production. 2. According to chest X-ray fíndíngs, moderately advanced 47.8%, far aclvanced 48.8% and wíth cavítíes was 79. 2%. 3. Bacteríologically positive at time of admission was 80. 7%. Among those primary resistant to one or more of the standard drugs 37. 5%, sensítive to three drugs 62. 5 % ín no previous chemotherapy group and 84. 8 %, 15. 2% in prevlously treated group. This would indicate acquired resistance is very high among patient who medicated themselves before admission to the hospital.