STUDY ON RESISTANCE OF THE ANTITUBERCULOUS DRUGS RESISTANT TUBERCLE BACILLl OF THE PHYSlCAL AND CHEMICAL AGENTS IV. Experiments on the Cross-resistance of One Drug-resistant Tubercle Bacilli to other Antituberculous Agents:

Kim, Kyung Soo

doi:1964.0.17.15

Tuberc Respir Dis > Issue 17; 1964 > Article

Tuberculosis and Respiratory Diseases 1964;17:15-18.
DOI: https://doi.org/10.4046/trd.1964.17.1.15 Published online December 1, 1964.

STUDY ON RESISTANCE OF THE ANTITUBERCULOUS DRUGS RESISTANT TUBERCLE BACILLl OF THE PHYSlCAL AND CHEMICAL AGENTS IV. Experiments on the Cross-resistance of One Drug-resistant Tubercle Bacilli to other Antituberculous Agents:

Kyung Soo Kim

Department of Preventive Medicine Kyung-Pook University School of Medicine

Abstract

The cross-resistance of strains resistant to 10R, 100r and 1000r per ml of SM and PAS and Ravenal strains resistant to 1r, 10r, 100r of INH were tested according to the primary step selection method. 1. Generally high cross-resistance was noted in the resistant strains in comparison with the sensitive strains. 2. INH-resistant strains showed relatively strong resistance to SM, while SM-resistant strains to PAS and INH. 3. Among anti-tuberculous agents. the order of high degree cross-resistance was as follows: SM, PAS and INH.