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Tuberc Respir Dis > Volume 40(4); 1993 > Article
Original Article
Tuberculosis and Respiratory Diseases 1993;40(4):404-409.
DOI: https://doi.org/10.4046/trd.1993.40.4.404    Published online August 1, 1993.
The clinical aspects of pulmonary tuberculosis patient failed in retreatment.
Young Jae Im, Ju Young Song, Jae Man Jeong, Young Jun Kim, Moon Shik Kim
Korea Kongju Tuberculosis Hospital, Kongju, Korea
Abstract
Background
There are many retreatment failure patients admitted in National Kongju Tuberculosis Hospital. But there is not satisfactory treatment method for them at present. We think that more attentions and active measures for them are needed.
Methods
We reviewed sex and age, duration of illness, previously used antituberculosis drugs, drug resistance, extent of disease, reasons for eariy stopping or irregular medication and schooling of 50 retreatment failure patients admitted in National Kongju Tuberculosis Hospital from April 1992 to February 1993.
Results
1) The male to female ratio was 3:2 and 62% of the patients were between 21 and 40 years of age. 2) Twenty eight cases (56%) had the duration of illness over 10 years 3) All cases had used most of the antituberculosis drugs 4) Drug sensitivity test showed resistance to RMP in 46 cases (96%), INH in 40 cases (83%) and other drugs in 3-32 cases (6-67%). 5) Forty eight cases (96%) had far advanced disease on chest P-A film. 6) Twenty eight cases (56%) in primary chemotherapy and twenty one cases (42%) in retreatment had the histories of premature stopping or irregular ingestion of the drug. The reasons for premature stopping or irregular ingestion of the drug were as follows; in primary chemotherapy , 29 cases (75%) were due to ‘having no symptoms’, while in retreatment, 6 cases (29%) were due to ‘having no symtoms’, 6 cases (29%) were ‘too busy' and 3 cases (1 4%) were for ‘financial problem'. 7) Twenty seven cases (54%) had at least graduated from high school.
Conclusion
Greater efforts are needed to prevent tratment failure. More supports and admission treatment for retreatment failure patients are needed to prevent infection and to treat properly.
Key Words: Pulmonary Tuberculosis, Retreatment Failure
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