A case of rhabdomyosarcoma arising at the pleura. |
Jin Goo Lee1, Kyung Mook Choi1, Sang Won Shin1, Kwang Ho In1, Kyung Ho Kang1, Joon Seok Kim1, Se Hwa Yoo1, Nam Hee Won2, Yoon Seok Lee3 |
1Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea 2Department of Pathology, College of Medicine, Korea University, Seoul, Korea 3Department of Internal Medicine, Chunggoo General Hospital, Seoul, Korea |
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Abstract |
Although uncommon, rhabdomyosarcomas are one of the most frequent forms of cancer of soft
parts, particularly in children under the age of 15. There has been only one case of primary rhabdomyosarcoma arising at the pleura, reported by Hamada, Japan, 1989, in the world.
A case of primary rhabdomyosarcoma arising at the pleura is reported This 15-year-old male patient was admitted to the hospital due to a one-month history of dyspnea on exertion and massive right pleural effusion. Pleural biopsy revealed embryonal rhabdomyosarcoma histologically. Immunohistochemical study shows positive reactivity to desmin, vimentin, and cytokeratin. Ultrastructural demonstration of thin and thick myofilaments was most helpful for confirming the histopathological diagnosis. The patient was received 6 cycles of chemotherapy with adriamycin, cyclophosphamide, vincristine and dacarbazine. The chemotherapy response was fairly good that the patient’s symptom was absent and pleural effusion and mass size was improved 6 months after chemotherapy This paper reports the second case of primary rhabdomyosarcoma of the pleura in the world with the review of literature. |
Key Words:
Rhabdomyosarcoma, Pleura, Chemotheherapy |
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